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Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer
BACKGROUND: Patients often ask oncologists how long a cancer has been present before causing symptoms or spreading to other organs. The evolutionary trajectory of cancers can be defined using phylogenetic approaches but lack of chronological references makes dating the exact onset of tumours very ch...
Autores principales: | Lote, H., Spiteri, I., Ermini, L., Vatsiou, A., Roy, A., McDonald, A., Maka, N., Balsitis, M., Bose, N., Simbolo, M., Mafficini, A., Lampis, A., Hahne, J. C., Trevisani, F., Eltahir, Z., Mentrasti, G., Findlay, C., Kalkman, E. A. J., Punta, M., Werner, B., Lise, S., Aktipis, A., Maley, C., Greaves, M., Braconi, C., White, J., Fassan, M., Scarpa, A., Sottoriva, A., Valeri, N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452067/ https://www.ncbi.nlm.nih.gov/pubmed/28327965 http://dx.doi.org/10.1093/annonc/mdx074 |
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