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Tradeoff-in-the-Nephron: A Theory to Explain the Primacy of Phosphate in the Pathogenesis of Secondary Hyperparathyroidism

Chronic kidney disease (CKD) causes secondary hyperparathyroidism (SHPT). The cardinal features of SHPT are persistence of normocalcemia as CKD progresses and dependence of the parathyroid hormone concentration ([PTH]) on phosphate influx (I(P)). The tradeoff-in-the-nephron hypothesis integrates the...

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Detalles Bibliográficos
Autor principal:	Phelps, Kenneth R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Concept Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452157/ https://www.ncbi.nlm.nih.gov/pubmed/28445401 http://dx.doi.org/10.3390/nu9050427

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