The Neuroprotective Effects of Phenolic Acids: Molecular Mechanism of Action

The neuroprotective role of phenolic acids from food has previously been reported by many authors. In this review, the role of phenolic acids in ameliorating depression, ischemia/reperfusion injury, neuroinflammation, apoptosis, glutamate-induced toxicity, epilepsy, imbalance after traumatic brain i...

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Autores principales: Szwajgier, Dominik, Borowiec, Kamila, Pustelniak, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452207/
https://www.ncbi.nlm.nih.gov/pubmed/28489058
http://dx.doi.org/10.3390/nu9050477
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author Szwajgier, Dominik
Borowiec, Kamila
Pustelniak, Katarzyna
author_facet Szwajgier, Dominik
Borowiec, Kamila
Pustelniak, Katarzyna
author_sort Szwajgier, Dominik
collection PubMed
description The neuroprotective role of phenolic acids from food has previously been reported by many authors. In this review, the role of phenolic acids in ameliorating depression, ischemia/reperfusion injury, neuroinflammation, apoptosis, glutamate-induced toxicity, epilepsy, imbalance after traumatic brain injury, hyperinsulinemia-induced memory impairment, hearing and vision disturbances, Parkinson’s disease, Huntington’s disease, anti-amyotrophic lateral sclerosis, Chagas disease and other less distributed diseases is discussed. This review covers the in vitro, ex vivo and in vivo studies concerning the prevention and treatment of neurological disorders (on the biochemical and gene expression levels) by phenolic acids.
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spelling pubmed-54522072017-06-05 The Neuroprotective Effects of Phenolic Acids: Molecular Mechanism of Action Szwajgier, Dominik Borowiec, Kamila Pustelniak, Katarzyna Nutrients Article The neuroprotective role of phenolic acids from food has previously been reported by many authors. In this review, the role of phenolic acids in ameliorating depression, ischemia/reperfusion injury, neuroinflammation, apoptosis, glutamate-induced toxicity, epilepsy, imbalance after traumatic brain injury, hyperinsulinemia-induced memory impairment, hearing and vision disturbances, Parkinson’s disease, Huntington’s disease, anti-amyotrophic lateral sclerosis, Chagas disease and other less distributed diseases is discussed. This review covers the in vitro, ex vivo and in vivo studies concerning the prevention and treatment of neurological disorders (on the biochemical and gene expression levels) by phenolic acids. MDPI 2017-05-10 /pmc/articles/PMC5452207/ /pubmed/28489058 http://dx.doi.org/10.3390/nu9050477 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Szwajgier, Dominik
Borowiec, Kamila
Pustelniak, Katarzyna
The Neuroprotective Effects of Phenolic Acids: Molecular Mechanism of Action
title The Neuroprotective Effects of Phenolic Acids: Molecular Mechanism of Action
title_full The Neuroprotective Effects of Phenolic Acids: Molecular Mechanism of Action
title_fullStr The Neuroprotective Effects of Phenolic Acids: Molecular Mechanism of Action
title_full_unstemmed The Neuroprotective Effects of Phenolic Acids: Molecular Mechanism of Action
title_short The Neuroprotective Effects of Phenolic Acids: Molecular Mechanism of Action
title_sort neuroprotective effects of phenolic acids: molecular mechanism of action
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452207/
https://www.ncbi.nlm.nih.gov/pubmed/28489058
http://dx.doi.org/10.3390/nu9050477
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