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Rotational restriction of nascent peptides as an essential element of co-translational protein folding: possible molecular players and structural consequences
BACKGROUND: A basic tenet of protein science is that all information about the spatial structure of proteins is present in their sequences. Nonetheless, many proteins fail to attain native structure upon experimental denaturation and refolding in vitro, raising the question of the specific role of c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452302/ https://www.ncbi.nlm.nih.gov/pubmed/28569180 http://dx.doi.org/10.1186/s13062-017-0186-1 |