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Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells
BACKGROUND: Shikonin, a natural naphthoquinone pigment purified from Lithospermum erythrorhizon, induces necroptosis in various cancer types, but the mechanisms underlying the anticancer activity of shikonin in lung cancer are not fully understood. This study was designed to clarify whether shikonin...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452303/ https://www.ncbi.nlm.nih.gov/pubmed/28569199 http://dx.doi.org/10.1186/s12967-017-1223-7 |