Cargando…
Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells
BACKGROUND: Shikonin, a natural naphthoquinone pigment purified from Lithospermum erythrorhizon, induces necroptosis in various cancer types, but the mechanisms underlying the anticancer activity of shikonin in lung cancer are not fully understood. This study was designed to clarify whether shikonin...
Autores principales: | Kim, Hyo-Jin, Hwang, Ki-Eun, Park, Do-Sim, Oh, Seon-Hee, Jun, Hong Young, Yoon, Kwon-Ha, Jeong, Eun-Taik, Kim, Hak-Ryul, Kim, Young-Suk |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452303/ https://www.ncbi.nlm.nih.gov/pubmed/28569199 http://dx.doi.org/10.1186/s12967-017-1223-7 |
Ejemplares similares
-
Inhibition of autophagy potentiates pemetrexed and simvastatin-induced apoptotic cell death in malignant mesothelioma and non-small cell lung cancer cells
por: Hwang, Ki-Eun, et al.
Publicado: (2015) -
Pleural fluid characteristics of pleuropulmonary paragonimiasis masquerading as pleural tuberculosis
por: Hwang, Ki-Eun, et al.
Publicado: (2015) -
Celecoxib and sulindac inhibit TGF-β1-induced epithelial-mesenchymal transition and suppress lung cancer migration and invasion via downregulation of sirtuin 1
por: Cha, Byong-Ki, et al.
Publicado: (2016) -
Salinomycin suppresses TGF-β1-induced EMT by down-regulating MMP-2 and MMP-9 via the AMPK/SIRT1 pathway in non-small cell lung cancer
por: Hwang, Ki-Eun, et al.
Publicado: (2021) -
Synergistic Effect of Sulindac and Simvastatin on Apoptosis in Lung Cancer A549 Cells through AKT-Dependent Downregulation of Survivin
por: Kim, Young-Suk, et al.
Publicado: (2015)