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Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells

BACKGROUND: Shikonin, a natural naphthoquinone pigment purified from Lithospermum erythrorhizon, induces necroptosis in various cancer types, but the mechanisms underlying the anticancer activity of shikonin in lung cancer are not fully understood. This study was designed to clarify whether shikonin...

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Detalles Bibliográficos
Autores principales: Kim, Hyo-Jin, Hwang, Ki-Eun, Park, Do-Sim, Oh, Seon-Hee, Jun, Hong Young, Yoon, Kwon-Ha, Jeong, Eun-Taik, Kim, Hak-Ryul, Kim, Young-Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452303/
https://www.ncbi.nlm.nih.gov/pubmed/28569199
http://dx.doi.org/10.1186/s12967-017-1223-7

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