Spondylodiscitis in a healthy 12-year-old girl with Extraintestinal pathogenic Escherichia coli (ExPEC) bacteraemia

BACKGROUND: Escherichia coli (E. coli) is rarely implicated in bone or joint infections in children. CASE PRESENTATION: We discuss the case of a healthy 12-year-old girl with an E. coli bacteraemia and a T11-T12 spondylodiscitis revealed by magnetic resonance imaging. The strain harboured serogroup...

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Autores principales: Gaschignard, J., Geslain, G., Mallet, C., Lorrot, M., Blot, N., Alison, M., Bonacorsi, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452335/
https://www.ncbi.nlm.nih.gov/pubmed/28569143
http://dx.doi.org/10.1186/s12879-017-2486-6
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author Gaschignard, J.
Geslain, G.
Mallet, C.
Lorrot, M.
Blot, N.
Alison, M.
Bonacorsi, S.
author_facet Gaschignard, J.
Geslain, G.
Mallet, C.
Lorrot, M.
Blot, N.
Alison, M.
Bonacorsi, S.
author_sort Gaschignard, J.
collection PubMed
description BACKGROUND: Escherichia coli (E. coli) is rarely implicated in bone or joint infections in children. CASE PRESENTATION: We discuss the case of a healthy 12-year-old girl with an E. coli bacteraemia and a T11-T12 spondylodiscitis revealed by magnetic resonance imaging. The strain harboured serogroup O1:K1 and virulence factors common to highly virulent extra intestinal pathogenic E. coli (ExPEC). Immunological work-up was normal. CONCLUSION: The identification of E. coli in a spondylodiscitis should lead to the search for immunosuppression of the host and virulence factors of the strain, particularly those of ExPEC.
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spelling pubmed-54523352017-06-01 Spondylodiscitis in a healthy 12-year-old girl with Extraintestinal pathogenic Escherichia coli (ExPEC) bacteraemia Gaschignard, J. Geslain, G. Mallet, C. Lorrot, M. Blot, N. Alison, M. Bonacorsi, S. BMC Infect Dis Case Report BACKGROUND: Escherichia coli (E. coli) is rarely implicated in bone or joint infections in children. CASE PRESENTATION: We discuss the case of a healthy 12-year-old girl with an E. coli bacteraemia and a T11-T12 spondylodiscitis revealed by magnetic resonance imaging. The strain harboured serogroup O1:K1 and virulence factors common to highly virulent extra intestinal pathogenic E. coli (ExPEC). Immunological work-up was normal. CONCLUSION: The identification of E. coli in a spondylodiscitis should lead to the search for immunosuppression of the host and virulence factors of the strain, particularly those of ExPEC. BioMed Central 2017-05-31 /pmc/articles/PMC5452335/ /pubmed/28569143 http://dx.doi.org/10.1186/s12879-017-2486-6 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Gaschignard, J.
Geslain, G.
Mallet, C.
Lorrot, M.
Blot, N.
Alison, M.
Bonacorsi, S.
Spondylodiscitis in a healthy 12-year-old girl with Extraintestinal pathogenic Escherichia coli (ExPEC) bacteraemia
title Spondylodiscitis in a healthy 12-year-old girl with Extraintestinal pathogenic Escherichia coli (ExPEC) bacteraemia
title_full Spondylodiscitis in a healthy 12-year-old girl with Extraintestinal pathogenic Escherichia coli (ExPEC) bacteraemia
title_fullStr Spondylodiscitis in a healthy 12-year-old girl with Extraintestinal pathogenic Escherichia coli (ExPEC) bacteraemia
title_full_unstemmed Spondylodiscitis in a healthy 12-year-old girl with Extraintestinal pathogenic Escherichia coli (ExPEC) bacteraemia
title_short Spondylodiscitis in a healthy 12-year-old girl with Extraintestinal pathogenic Escherichia coli (ExPEC) bacteraemia
title_sort spondylodiscitis in a healthy 12-year-old girl with extraintestinal pathogenic escherichia coli (expec) bacteraemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452335/
https://www.ncbi.nlm.nih.gov/pubmed/28569143
http://dx.doi.org/10.1186/s12879-017-2486-6
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