Assessing the anthelmintic activity of pyrazole-5-carboxamide derivatives against Haemonchus contortus

BACKGROUND: In this study, we tested five series of pyrazole-5-carboxamide compounds (n = 55) for activity against parasitic stages of the nematode Haemonchus contortus (barber’s pole worm), one of the most pathogenic parasites of ruminants. METHODS: In an optimised, whole-organism screening assay,...

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Detalles Bibliográficos
Autores principales: Jiao, Yaqing, Preston, Sarah, Song, Hongjian, Jabbar, Abdul, Liu, Yuxiu, Baell, Jonathan, Hofmann, Andreas, Hutchinson, Dana, Wang, Tao, Koehler, Anson V., Fisher, Gillian M., Andrews, Katherine T., Laleu, Benoît, Palmer, Michael J., Burrows, Jeremy N., Wells, Timothy N. C., Wang, Qingmin, Gasser, Robin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452367/
https://www.ncbi.nlm.nih.gov/pubmed/28569174
http://dx.doi.org/10.1186/s13071-017-2191-8

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