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In-vivo monitoring of anti-folate therapy in arthritic rats using [(18)F]fluoro-PEG-folate and positron emission tomography

BACKGROUND: Folate receptor β (FRβ) is involved in facilitating cellular uptake of folates and anti-folates (such as methotrexate (MTX)). In rheumatoid arthritis, FRβ is expressed on synovial macrophages and recently has been explored as a biomarker for imaging in arthritic rats using the folate-bas...

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Detalles Bibliográficos
Autores principales:	Chandrupatla, Durga M. S. H., Jansen, Gerrit, Vos, Ricardo, Verlaan, Mariska, Chen, Qingshou, Low, Philip S., Windhorst, Albert D., Lammertsma, Adriaan A., van der Laken, Conny J., Molthoff, Carla F. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452381/ https://www.ncbi.nlm.nih.gov/pubmed/28569209 http://dx.doi.org/10.1186/s13075-017-1325-x

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