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Giemsa-stained pseudo-micronuclei in rat skin treated with vitamin D(3) analog, pefcalcitol

BACKGROUND: Pefcalcitol, an analog of vitamin D(3) (VD(3)), is an anti-psoriatic drug candidate that is designed to achieve much higher pharmacological effects, such as keratinocyte differentiation, than those of VD(3,) with fewer side effects. Genotoxicity of the compound was evaluated in a rat ski...

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Detalles Bibliográficos
Autores principales:	Takeiri, Akira, Tanaka, Kenji, Harada, Asako, Matsuzaki, Kaori, Yano, Mariko, Motoyama, Shigeki, Katoh, Chie, Mishima, Masayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452393/ https://www.ncbi.nlm.nih.gov/pubmed/28580039 http://dx.doi.org/10.1186/s41021-017-0077-9

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