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BRCA promoter methylation in sporadic versus BRCA germline mutation-related breast cancers
BACKGROUND: In breast cancer, BRCA promoter hypermethylation and BRCA germline mutations are said to occur together rarely, but this property has not yet been translated into a clinical test. Our aim in this study was to investigate the diagnostic value of BRCA1/2 methylation in distinguishing breas...
Autores principales: | Vos, Shoko, Moelans, Cathy Beatrice, van Diest, Paul Joannes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452400/ https://www.ncbi.nlm.nih.gov/pubmed/28569220 http://dx.doi.org/10.1186/s13058-017-0856-z |
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