Hemophagocytic Lymphohistiocytosis Associated with Anaplasmosis

Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome characterized by unregulated macrophage and T-lymphocyte activation resulting in cytokine overproduction and subsequent histiocytic phagocytosis. Variant infections, particularly viruses have been postulated as the inciting fac...

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Autores principales: Johnson, Tamara M, Brown, Melinda S, Rabbat, Mohamed, Slim, Jihad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452556/
https://www.ncbi.nlm.nih.gov/pubmed/28584460
http://dx.doi.org/10.4103/jgid.jgid_116_16
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author Johnson, Tamara M
Brown, Melinda S
Rabbat, Mohamed
Slim, Jihad
author_facet Johnson, Tamara M
Brown, Melinda S
Rabbat, Mohamed
Slim, Jihad
author_sort Johnson, Tamara M
collection PubMed
description Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome characterized by unregulated macrophage and T-lymphocyte activation resulting in cytokine overproduction and subsequent histiocytic phagocytosis. Variant infections, particularly viruses have been postulated as the inciting factor for this potentially fatal disease. Herein, we will report a case of HLH associated with anaplasmosis.
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spelling pubmed-54525562017-06-05 Hemophagocytic Lymphohistiocytosis Associated with Anaplasmosis Johnson, Tamara M Brown, Melinda S Rabbat, Mohamed Slim, Jihad J Glob Infect Dis Case Report Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome characterized by unregulated macrophage and T-lymphocyte activation resulting in cytokine overproduction and subsequent histiocytic phagocytosis. Variant infections, particularly viruses have been postulated as the inciting factor for this potentially fatal disease. Herein, we will report a case of HLH associated with anaplasmosis. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5452556/ /pubmed/28584460 http://dx.doi.org/10.4103/jgid.jgid_116_16 Text en Copyright: © 2017 Journal of Global Infectious Diseases http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Johnson, Tamara M
Brown, Melinda S
Rabbat, Mohamed
Slim, Jihad
Hemophagocytic Lymphohistiocytosis Associated with Anaplasmosis
title Hemophagocytic Lymphohistiocytosis Associated with Anaplasmosis
title_full Hemophagocytic Lymphohistiocytosis Associated with Anaplasmosis
title_fullStr Hemophagocytic Lymphohistiocytosis Associated with Anaplasmosis
title_full_unstemmed Hemophagocytic Lymphohistiocytosis Associated with Anaplasmosis
title_short Hemophagocytic Lymphohistiocytosis Associated with Anaplasmosis
title_sort hemophagocytic lymphohistiocytosis associated with anaplasmosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452556/
https://www.ncbi.nlm.nih.gov/pubmed/28584460
http://dx.doi.org/10.4103/jgid.jgid_116_16
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AT slimjihad hemophagocyticlymphohistiocytosisassociatedwithanaplasmosis

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