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Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine
BACKGROUND: The sexual stages of Plasmodium falciparum are responsible for the spread of the parasite in malaria endemic areas. The cysteine-rich Pfs48/45 protein, exposed on the surface of sexual stages, is one of the most advanced antigens for inclusion into a vaccine that will block transmission....
Autores principales: | Singh, Susheel K., Roeffen, Will, Mistarz, Ulrik H., Chourasia, Bishwanath Kumar, Yang, Fen, Rand, Kasper D., Sauerwein, Robert W., Theisen, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452637/ https://www.ncbi.nlm.nih.gov/pubmed/28569168 http://dx.doi.org/10.1186/s12934-017-0710-0 |
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