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Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine

BACKGROUND: The sexual stages of Plasmodium falciparum are responsible for the spread of the parasite in malaria endemic areas. The cysteine-rich Pfs48/45 protein, exposed on the surface of sexual stages, is one of the most advanced antigens for inclusion into a vaccine that will block transmission....

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Detalles Bibliográficos
Autores principales: Singh, Susheel K., Roeffen, Will, Mistarz, Ulrik H., Chourasia, Bishwanath Kumar, Yang, Fen, Rand, Kasper D., Sauerwein, Robert W., Theisen, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452637/
https://www.ncbi.nlm.nih.gov/pubmed/28569168
http://dx.doi.org/10.1186/s12934-017-0710-0

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