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Synergistic activity of the histone deacetylase inhibitor trichostatin A and the proteasome inhibitor PS-341 against taxane-resistant ovarian cancer cell lines

Although a combination of platinum- and taxane-based chemotherapy is recommended for at least 70% patients with ovarian cancer as treatment subsequent to surgery, the initial response to the chemotherapy is not durable and tumors become resistant. Histone deacetylase and proteasome inhibitors are no...

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Detalles Bibliográficos
Autores principales: Jin, Xin, Fang, Yong, Hu, Yi, Chen, Jing, Liu, Wei, Chen, Gang, Gong, Mei, Wu, Peng, Zhu, Tao, Wang, Shixuan, Zhou, Jianfeng, Wang, Hui, Ma, Ding, Li, Kezhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452869/
https://www.ncbi.nlm.nih.gov/pubmed/28588720
http://dx.doi.org/10.3892/ol.2017.6032

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