Cargando…

MAPK/P53-mediated FASN expression in bone tumors

The correlation between mitogen-activated protein kinase (MAPK)/P53 signaling-dependent fatty acid synthase (FASN) expression and bone tumors was examined in the present study. We established the SH081 bone tumor cell line, which was used to determine the expression of FASN and MAPK/P53 at the mRNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Ye, Yin, Xiaofan, Wu, Liang, Qin, Qiang, Xu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452927/ https://www.ncbi.nlm.nih.gov/pubmed/28588696 http://dx.doi.org/10.3892/ol.2017.6015

Ejemplares similares

Derepression of the USP22-FASN axis by p53 loss under oxidative stress drives lipogenesis and tumorigenesis
por: Han, Zelong, et al.
Publicado: (2022)

FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and Gene Expression
por: Heuer, Timothy S., et al.
Publicado: (2016)

Enhanced De Novo Lipid Synthesis Mediated by FASN Induces Chemoresistance in Colorectal Cancer
por: Han, Lingyu, et al.
Publicado: (2023)

FABP5 suppresses colorectal cancer progression via mTOR-mediated autophagy by decreasing FASN expression
por: Ye, Mujie, et al.
Publicado: (2023)

Identification of Acetylation Sites of Fatty Acid Synthase (FASN) by Mass Spectrometry and FASN Activity Assay
por: Miao, Ting, et al.
Publicado: (2023)

Anoikis resistant mediated by FASN promoted growth and metastasis of osteosarcoma
por: Sun, Tianhao, et al.
Publicado: (2019)

KDM5C Represses FASN-Mediated Lipid Metabolism to Exert Tumor Suppressor Activity in Intrahepatic Cholangiocarcinoma
por: Zhang, Bo, et al.
Publicado: (2020)

FASN-Mediated Lipid Metabolism Regulates Goose Granulosa Cells Apoptosis and Steroidogenesis
por: Chen, Xi, et al.
Publicado: (2020)

FBXW7β loss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth
por: Wei, Wenxia, et al.
Publicado: (2023)

Anlotinib suppresses lung adenocarcinoma growth via inhibiting FASN-mediated lipid metabolism
por: Shen, Juan, et al.
Publicado: (2022)

FASN expression, angiogenesis and lymphangiogenesis in central and peripheral giant cell lesions
por: FALCI, Saulo Gabriel Moreira, et al.
Publicado: (2014)

The fasn-1(g14ts) allele is a Gly1830Arg missense mutation in C. elegans FASN-1
por: Bai, Xiaofei, et al.
Publicado: (2020)

Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy
por: Humbert, Magali, et al.
Publicado: (2021)

Modulation of Breast Cancer Cell FASN Expression by Obesity-Related Systemic Factors
por: McClellan, Bryan, et al.
Publicado: (2022)

FASN activity is important for the initial stages of the induction of senescence
por: Fafián-Labora, Juan, et al.
Publicado: (2019)

Cancer cells escape p53’s tumor suppression through ablation of ZDHHC1-mediated p53 palmitoylation
por: Tang, Jun, et al.
Publicado: (2021)

Inverse relation between FASN expression in human adipose tissue and the insulin resistance level
por: Mayas, María D, et al.
Publicado: (2010)

MACC1 decreases the chemosensitivity of gastric cancer cells to oxaliplatin by regulating FASN expression
por: Duan, Jiangman, et al.
Publicado: (2017)

FABP5 regulates lipid metabolism to facilitate pancreatic neuroendocrine neoplasms progression via FASN mediated Wnt/β‐catenin pathway
por: Lu, Feiyu, et al.
Publicado: (2023)

Long noncoding RNA SNHG25 promotes the malignancy of endometrial cancer by sponging microRNA-497-5p and increasing FASN expression
por: He, Yuhua, et al.
Publicado: (2021)

Comprehensive Analysis of FASN in Tumor Immune Infiltration and Prognostic Value for Immunotherapy and Promoter DNA Methylation
por: Zhang, Mingyang, et al.
Publicado: (2022)

p38α MAPK-mediated induction and interaction of FOXO3a and p53 contribute to the inhibited-growth and induced-apoptosis of human lung adenocarcinoma cells by berberine
por: Zheng, Fang, et al.
Publicado: (2014)

FASN-dependent de novo lipogenesis is required for brain development
por: Gonzalez-Bohorquez, Daniel, et al.
Publicado: (2022)

A FASN-TGF-β1-FASN regulatory loop contributes to high EMT/metastatic potential of cisplatin-resistant non-small cell lung cancer
por: Yang, Li, et al.
Publicado: (2016)

MET and FASN as Prognostic Biomarkers of Triple Negative Breast Cancer: A Systematic Evidence Landscape of Clinical Study
por: Jiang, Weihua, et al.
Publicado: (2021)

Up-Regulated FASN Expression Promotes Transcoelomic Metastasis of Ovarian Cancer Cell through Epithelial-Mesenchymal Transition
por: Jiang, Li, et al.
Publicado: (2014)

Exosomes derived from impaired liver aggravate alveolar bone loss via shuttle of Fasn in type 2 diabetes mellitus
por: Liu, Jiani, et al.
Publicado: (2023)

Role of microRNA-15a-5p in the atherosclerotic inflammatory response and arterial injury improvement of diabetic by targeting FASN
por: Liu, Yang, et al.
Publicado: (2019)

CircRREB1 mediates lipid metabolism related senescent phenotypes in chondrocytes through FASN post-translational modifications
por: Gong, Zhe, et al.
Publicado: (2023)

The m6A modification-mediated OGDHL exerts a tumor suppressor role in ccRCC by downregulating FASN to inhibit lipid synthesis and ERK signaling
por: Shi, Jian, et al.
Publicado: (2023)

Fasnall Induces Atypically Transient Stress Granules Independently of FASN Inhibition
por: Amen, Triana, et al.
Publicado: (2020)

FASN Is a Biomarker Enriched in Malignant Glioma-Derived Extracellular Vesicles
por: Ricklefs, Franz L., et al.
Publicado: (2020)

Metformin alleviates inflammation through suppressing FASN-dependent palmitoylation of Akt
por: Xiong, Wenfang, et al.
Publicado: (2021)

Fatty acid synthase (FASN) regulates the mitochondrial priming of cancer cells
por: Schroeder, Barbara, et al.
Publicado: (2021)

SREBP1/FASN/cholesterol axis facilitates radioresistance in colorectal cancer
por: Jin, Yuxiao, et al.
Publicado: (2021)

Concomitant Inhibition of FASN and SREBP Provides a Promising Therapy for CTCL
por: Chi, Cheng, et al.
Publicado: (2022)

Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth
por: Han, Anna, et al.
Publicado: (2023)

Calreticulin mediates an invasive breast cancer phenotype through the transcriptional dysregulation of p53 and MAPK pathways
por: Zamanian, Mohammadreza, et al.
Publicado: (2016)

FASN Protein Overexpression Indicates Poor Biochemical Recurrence-Free Survival in Prostate Cancer
por: Cao, Zhi, et al.
Publicado: (2020)

Prenatal caloric restriction alters lipid metabolism but not hepatic Fasn gene expression and methylation profiles in rats
por: Nowacka-Woszuk, Joanna, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_t7hh5boe4q94k14vvcaiuu88tq