Cargando…

KID Project: an internet-based digital video atlas of capsule endoscopy for research purposes

BACKGROUND AND AIMS:  Capsule endoscopy (CE) has revolutionized small-bowel (SB) investigation. Computational methods can enhance diagnostic yield (DY); however, incorporating machine learning algorithms (MLAs) into CE reading is difficult as large amounts of image annotations are required for train...

Descripción completa

Detalles Bibliográficos
Autores principales: Koulaouzidis, Anastasios, Iakovidis, Dimitris K., Yung, Diana E., Rondonotti, Emanuele, Kopylov, Uri, Plevris, John N., Toth, Ervin, Eliakim, Abraham, Wurm Johansson, Gabrielle, Marlicz, Wojciech, Mavrogenis, Georgios, Nemeth, Artur, Thorlacius, Henrik, Tontini, Gian Eugenio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: © Georg Thieme Verlag KG 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452962/
https://www.ncbi.nlm.nih.gov/pubmed/28580415
http://dx.doi.org/10.1055/s-0043-105488
_version_ 1783240548649271296
author Koulaouzidis, Anastasios
Iakovidis, Dimitris K.
Yung, Diana E.
Rondonotti, Emanuele
Kopylov, Uri
Plevris, John N.
Toth, Ervin
Eliakim, Abraham
Wurm Johansson, Gabrielle
Marlicz, Wojciech
Mavrogenis, Georgios
Nemeth, Artur
Thorlacius, Henrik
Tontini, Gian Eugenio
author_facet Koulaouzidis, Anastasios
Iakovidis, Dimitris K.
Yung, Diana E.
Rondonotti, Emanuele
Kopylov, Uri
Plevris, John N.
Toth, Ervin
Eliakim, Abraham
Wurm Johansson, Gabrielle
Marlicz, Wojciech
Mavrogenis, Georgios
Nemeth, Artur
Thorlacius, Henrik
Tontini, Gian Eugenio
author_sort Koulaouzidis, Anastasios
collection PubMed
description BACKGROUND AND AIMS:  Capsule endoscopy (CE) has revolutionized small-bowel (SB) investigation. Computational methods can enhance diagnostic yield (DY); however, incorporating machine learning algorithms (MLAs) into CE reading is difficult as large amounts of image annotations are required for training. Current databases lack graphic annotations of pathologies and cannot be used. A novel database, KID, aims to provide a reference for research and development of medical decision support systems (MDSS) for CE. METHODS:  Open-source software was used for the KID database. Clinicians contribute anonymized, annotated CE images and videos. Graphic annotations are supported by an open-access annotation tool (Ratsnake). We detail an experiment based on the KID database, examining differences in SB lesion measurement between human readers and a MLA. The Jaccard Index (JI) was used to evaluate similarity between annotations by the MLA and human readers. RESULTS:  The MLA performed best in measuring lymphangiectasias with a JI of 81 ± 6 %. The other lesion types were: angioectasias (JI 64 ± 11 %), aphthae (JI 64 ± 8 %), chylous cysts (JI 70 ± 14 %), polypoid lesions (JI 75 ± 21 %), and ulcers (JI 56 ± 9 %). CONCLUSION:  MLA can perform as well as human readers in the measurement of SB angioectasias in white light (WL). Automated lesion measurement is therefore feasible. KID is currently the only open-source CE database developed specifically to aid development of MDSS. Our experiment demonstrates this potential.
format Online
Article
Text
id pubmed-5452962
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher © Georg Thieme Verlag KG
record_format MEDLINE/PubMed
spelling pubmed-54529622017-06-02 KID Project: an internet-based digital video atlas of capsule endoscopy for research purposes Koulaouzidis, Anastasios Iakovidis, Dimitris K. Yung, Diana E. Rondonotti, Emanuele Kopylov, Uri Plevris, John N. Toth, Ervin Eliakim, Abraham Wurm Johansson, Gabrielle Marlicz, Wojciech Mavrogenis, Georgios Nemeth, Artur Thorlacius, Henrik Tontini, Gian Eugenio Endosc Int Open BACKGROUND AND AIMS:  Capsule endoscopy (CE) has revolutionized small-bowel (SB) investigation. Computational methods can enhance diagnostic yield (DY); however, incorporating machine learning algorithms (MLAs) into CE reading is difficult as large amounts of image annotations are required for training. Current databases lack graphic annotations of pathologies and cannot be used. A novel database, KID, aims to provide a reference for research and development of medical decision support systems (MDSS) for CE. METHODS:  Open-source software was used for the KID database. Clinicians contribute anonymized, annotated CE images and videos. Graphic annotations are supported by an open-access annotation tool (Ratsnake). We detail an experiment based on the KID database, examining differences in SB lesion measurement between human readers and a MLA. The Jaccard Index (JI) was used to evaluate similarity between annotations by the MLA and human readers. RESULTS:  The MLA performed best in measuring lymphangiectasias with a JI of 81 ± 6 %. The other lesion types were: angioectasias (JI 64 ± 11 %), aphthae (JI 64 ± 8 %), chylous cysts (JI 70 ± 14 %), polypoid lesions (JI 75 ± 21 %), and ulcers (JI 56 ± 9 %). CONCLUSION:  MLA can perform as well as human readers in the measurement of SB angioectasias in white light (WL). Automated lesion measurement is therefore feasible. KID is currently the only open-source CE database developed specifically to aid development of MDSS. Our experiment demonstrates this potential. © Georg Thieme Verlag KG 2017-06 2017-05-31 /pmc/articles/PMC5452962/ /pubmed/28580415 http://dx.doi.org/10.1055/s-0043-105488 Text en © Thieme Medical Publishers
spellingShingle Koulaouzidis, Anastasios
Iakovidis, Dimitris K.
Yung, Diana E.
Rondonotti, Emanuele
Kopylov, Uri
Plevris, John N.
Toth, Ervin
Eliakim, Abraham
Wurm Johansson, Gabrielle
Marlicz, Wojciech
Mavrogenis, Georgios
Nemeth, Artur
Thorlacius, Henrik
Tontini, Gian Eugenio
KID Project: an internet-based digital video atlas of capsule endoscopy for research purposes
title KID Project: an internet-based digital video atlas of capsule endoscopy for research purposes
title_full KID Project: an internet-based digital video atlas of capsule endoscopy for research purposes
title_fullStr KID Project: an internet-based digital video atlas of capsule endoscopy for research purposes
title_full_unstemmed KID Project: an internet-based digital video atlas of capsule endoscopy for research purposes
title_short KID Project: an internet-based digital video atlas of capsule endoscopy for research purposes
title_sort kid project: an internet-based digital video atlas of capsule endoscopy for research purposes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452962/
https://www.ncbi.nlm.nih.gov/pubmed/28580415
http://dx.doi.org/10.1055/s-0043-105488
work_keys_str_mv AT koulaouzidisanastasios kidprojectaninternetbaseddigitalvideoatlasofcapsuleendoscopyforresearchpurposes
AT iakovidisdimitrisk kidprojectaninternetbaseddigitalvideoatlasofcapsuleendoscopyforresearchpurposes
AT yungdianae kidprojectaninternetbaseddigitalvideoatlasofcapsuleendoscopyforresearchpurposes
AT rondonottiemanuele kidprojectaninternetbaseddigitalvideoatlasofcapsuleendoscopyforresearchpurposes
AT kopylovuri kidprojectaninternetbaseddigitalvideoatlasofcapsuleendoscopyforresearchpurposes
AT plevrisjohnn kidprojectaninternetbaseddigitalvideoatlasofcapsuleendoscopyforresearchpurposes
AT tothervin kidprojectaninternetbaseddigitalvideoatlasofcapsuleendoscopyforresearchpurposes
AT eliakimabraham kidprojectaninternetbaseddigitalvideoatlasofcapsuleendoscopyforresearchpurposes
AT wurmjohanssongabrielle kidprojectaninternetbaseddigitalvideoatlasofcapsuleendoscopyforresearchpurposes
AT marliczwojciech kidprojectaninternetbaseddigitalvideoatlasofcapsuleendoscopyforresearchpurposes
AT mavrogenisgeorgios kidprojectaninternetbaseddigitalvideoatlasofcapsuleendoscopyforresearchpurposes
AT nemethartur kidprojectaninternetbaseddigitalvideoatlasofcapsuleendoscopyforresearchpurposes
AT thorlaciushenrik kidprojectaninternetbaseddigitalvideoatlasofcapsuleendoscopyforresearchpurposes
AT tontinigianeugenio kidprojectaninternetbaseddigitalvideoatlasofcapsuleendoscopyforresearchpurposes