Calculating site-specific evolutionary rates at the amino-acid or codon level yields similar rate estimates

Site-specific evolutionary rates can be estimated from codon sequences or from amino-acid sequences. For codon sequences, the most popular methods use some variation of the dN∕dS ratio. For amino-acid sequences, one widely-used method is called Rate4Site, and it assigns a relative conservation score...

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Detalles Bibliográficos
Autores principales: Sydykova, Dariya K., Wilke, Claus O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452972/
https://www.ncbi.nlm.nih.gov/pubmed/28584717
http://dx.doi.org/10.7717/peerj.3391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452972/
https://www.ncbi.nlm.nih.gov/pubmed/28584717
http://dx.doi.org/10.7717/peerj.3391

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