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Downregulation of eIF4G by microRNA-503 enhances drug sensitivity of MCF-7/ADR cells through suppressing the expression of ABC transport proteins

Overexpression of adenosine triphosphate-binding cassette (ABC) transport protein is emerging as a critical contributor to anticancer drug resistance. The eukaryotic translation initiation factor (eIF) 4F complex, the key modulator of mRNA translation, is regulated by the phosphoinositide 3-kinase-A...

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Detalles Bibliográficos
Autores principales:	Pan, Xia, Yang, Xiaoyan, Zang, Jinglei, Zhang, Si, Huang, Nan, Guan, Xinxin, Zhang, Jianhua, Wang, Zhihui, Li, Xi, Lei, Xiaoyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453003/ https://www.ncbi.nlm.nih.gov/pubmed/28599480 http://dx.doi.org/10.3892/ol.2017.6049

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