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SPARC overexpression suppresses radiation-induced HSP27 and induces the collapse of mitochondrial Δψ in neuroblastoma cells

Neuroblastoma is the cause of >15% of cancer-associated mortality in children in the USA. Despite aggressive treatment regimens, the long-term survival rate for these children remains at <40%. The current study demonstrates that secreted protein acidic and rich in cysteine (SPARC) suppresses r...

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Detalles Bibliográficos
Autores principales: Tanpure, Smita, Boyineini, Jerusha, Gnanamony, Manu, Antony, Reuben, Fernández, Karen S., Libes, Jaime, Lin, Julian, Pinson, David, Joseph, Pushpa A., Gondi, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453037/
https://www.ncbi.nlm.nih.gov/pubmed/28599461
http://dx.doi.org/10.3892/ol.2017.6075

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