Cargando…
SPARC overexpression suppresses radiation-induced HSP27 and induces the collapse of mitochondrial Δψ in neuroblastoma cells
Neuroblastoma is the cause of >15% of cancer-associated mortality in children in the USA. Despite aggressive treatment regimens, the long-term survival rate for these children remains at <40%. The current study demonstrates that secreted protein acidic and rich in cysteine (SPARC) suppresses r...
Autores principales: | Tanpure, Smita, Boyineini, Jerusha, Gnanamony, Manu, Antony, Reuben, Fernández, Karen S., Libes, Jaime, Lin, Julian, Pinson, David, Joseph, Pushpa A., Gondi, Christopher S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453037/ https://www.ncbi.nlm.nih.gov/pubmed/28599461 http://dx.doi.org/10.3892/ol.2017.6075 |
Ejemplares similares
-
SPARC overexpression combined with radiation retards angiogenesis by suppressing VEGF-A via miR-410 in human neuroblastoma cells
por: Boyineni, Jerusha, et al.
Publicado: (2016) -
Chronic radiation exposure of neuroblastoma cells reduces nMYC copy number
por: Gnanamony, Manu, et al.
Publicado: (2017) -
The secreted protein acidic and rich in cysteine (SPARC) induces endoplasmic reticulum stress leading to autophagy-mediated apoptosis in neuroblastoma
por: SAILAJA, G.S., et al.
Publicado: (2012) -
SPARC Overexpression Inhibits Cell Proliferation in Neuroblastoma and Is Partly Mediated by Tumor Suppressor Protein PTEN and AKT
por: Bhoopathi, Praveen, et al.
Publicado: (2012) -
Circular dumbbell miR-34a-3p and −5p suppresses pancreatic tumor cell-induced angiogenesis and activates macrophages
por: Gnanamony, Manu, et al.
Publicado: (2021)