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Induction of cathepsin B by the CXCR3 chemokines CXCL9 and CXCL10 in human breast cancer cells

Cathepsin B (CTSB) is a lysosomal cysteine protease that has been linked to the progression of breast cancer, for example by activation of other proteases and tumor-promoting cytokines, thereby supporting tumor invasion and metastasis. Previously, it was shown that CTSB cleaves and inactivates C-X-C...

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Detalles Bibliográficos
Autores principales: Bronger, Holger, Karge, Anne, Dreyer, Tobias, Zech, Daniela, Kraeft, Sara, Avril, Stefanie, Kiechle, Marion, Schmitt, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453043/
https://www.ncbi.nlm.nih.gov/pubmed/28599423
http://dx.doi.org/10.3892/ol.2017.5994