Cargando…

Acute promyelocytic leukemia with a cryptic insertion of RARA into PML on chromosome 15 due to uniparental isodisomy: A case report

Acute promyelocytic leukemia is a myeloid disorder that is characterized by the specific t(15;17) variant in ~98% of cases. The typical hypergranular and microgranular or hypogranular types exist, and are frequently associated with disseminated intravascular coagulopathy. Rare cases of promyelocytic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Venci, Anna, Mazza, Rita, Spinelli, Orietta, Di Schiena, Luciana, Bettio, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453168/ https://www.ncbi.nlm.nih.gov/pubmed/28599418 http://dx.doi.org/10.3892/ol.2017.5979

Ejemplares similares

Characterization of cryptic rearrangements, deletion, complex variants of PML, RARA in acute promyelocytic leukemia
por: Amare, Pratibha Kadam, et al.
Publicado: (2011)

Cytogenetically cryptic PML::RARA fusion in acute promyelocytic leukemia: Testing strategies in the modern era
por: Karlin, Kirill, et al.
Publicado: (2022)

Educational Case: Acute Promyelocytic Leukemia With PML-RARA
por: Kunak, Rebecca L., et al.
Publicado: (2019)

Molecular methods for genomic analyses of variant PML-RARA or other RARA-related chromosomal translocations in acute promyelocytic leukemia
por: Kim, Min Jin, et al.
Publicado: (2012)

Absolute quantification of the pretreatment PML-RARA transcript defines the relapse risk in acute promyelocytic leukemia
por: Albano, Francesco, et al.
Publicado: (2015)

FISH Detection of PML-RARA Fusion in ins(15;17) Acute Promyelocytic Leukaemia Depends on Probe Size
por: Campbell, Lynda J., et al.
Publicado: (2013)

Chromosomal abnormality of acute promyelocytic leukemia other than PML-RARA: a case report of acute promyelocytic leukemia with del(5q)
por: Imataki, Osamu, et al.
Publicado: (2016)

The PML-RARA fusion is not detectable in historical blood samples of acute promyelocytic leukaemia patients
por: Dunn, William G., et al.
Publicado: (2021)

HNRNPC-RARA Fusion Gene in a Case with Acute Promyelocytic Leukemia Lacking PML-RARA Rearrangement Presenting with Abundant Hemophagocytosis
por: Tan, Jing, et al.
Publicado: (2023)

Expression and Function of PML-RARA in the Hematopoietic Progenitor Cells of Ctsg-PML-RARA Mice
por: Wartman, Lukas D., et al.
Publicado: (2012)

Paternal Uniparental Isodisomy of Chromosome 11p15.5 within the Pancreas Causes Isolated Hyperinsulinemic Hypoglycemia
por: Flanagan, S. E., et al.
Publicado: (2011)

Maternal uniparental isodisomy for chromosome 6 discovered by paternity testing: a case report
por: Kerr, Elizabeth R., et al.
Publicado: (2018)

Case Report: Paternal Uniparental Isodisomy and Heterodisomy of Chromosome 16 With a Normal Phenotype
por: Zhang, Xu, et al.
Publicado: (2021)

Prenatal diagnosis of complete paternal uniparental isodisomy for chromosome 3: a case report
por: Bu, Xiufen, et al.
Publicado: (2021)

Prenatal diagnosis and genetic counseling of a uniparental isodisomy of chromosome 8 with no phenotypic abnormalities
por: Yu, Chunjiao, et al.
Publicado: (2022)

Double paternal uniparental isodisomy 7 and 15 presenting with Beckwith–Wiedemann spectrum features
por: Berland, Siren, et al.
Publicado: (2021)

Early Detection of t(8;21) Chromosomal Translocations During Treatment of PML-RARA Positive Acute Promyelocytic Leukemia: A Case Study
por: Neto, Walter Kleine, et al.
Publicado: (2010)

Synergy against PML-RARa: targeting transcription, proteolysis, differentiation, and self-renewal in acute promyelocytic leukemia
por: dos Santos, Guilherme Augusto, et al.
Publicado: (2013)

High-Risk Microgranular Acute Promyelocytic Leukemia with a Five-Way Complex Translocation Involving PML-RARA
por: Powers, Benjamin, et al.
Publicado: (2015)

Identification of the novel deletion-type PML-RARA mutation associated with the retinoic acid resistance in acute promyelocytic leukemia
por: Hattori, Hikaru, et al.
Publicado: (2018)

PML-RARA Fusion Transcripts Detectable 8 Months prior to Promyelocytic Blast Crisis in Chronic Myeloid Leukemia
por: Wolanin, Stephanie, et al.
Publicado: (2020)

Acute Promyelocytic Leukemia: A Constellation of Molecular Events around a Single PML-RARA Fusion Gene
por: Liquori, Alessandro, et al.
Publicado: (2020)

PML/RARa Interferes with NRF2 Transcriptional Activity Increasing the Sensitivity to Ascorbate of Acute Promyelocytic Leukemia Cells
por: Banella, Cristina, et al.
Publicado: (2019)

Uniparental isodisomy of chromosome 1 results in glycogen storage disease type III with profound growth retardation
por: Ponzi, Emanuela, et al.
Publicado: (2019)

Paternal Uniparental Isodisomy of Chromosome 2 in a Patient with CNGA3-Associated Autosomal Recessive Achromatopsia
por: Kohl, Susanne, et al.
Publicado: (2021)

PARK7-Related Early Onset Parkinson Disease in the Setting of Complete Uniparental Isodisomy of Chromosome 1
por: Xiao, Changrui, et al.
Publicado: (2021)

Development of Flow Cytometry-Fluorescent In Situ Hybridization (Flow-FISH) Method for Detection of PML/RARa Chromosomal Translocation in Acute Promyelocytic Leukemia Cell Line
por: Zahedipour, Fatemeh, et al.
Publicado: (2017)

A complex translocation (1;17;15) with spliced short-type PML-RARA fusion transcripts in acute promyelocytic leukemia: A case report
por: Lv, Lili, et al.
Publicado: (2019)

Flow cytometric immunobead assay for fast and easy detection of PML–RARA fusion proteins for the diagnosis of acute promyelocytic leukemia
por: Dekking, E H A, et al.
Publicado: (2012)

Multi-omics and machine learning reveal context-specific gene regulatory activities of PML::RARA in acute promyelocytic leukemia
por: Villiers, William, et al.
Publicado: (2023)

Mucopolysaccharidosis type I due to maternal uniparental disomy of chromosome 4 with partial isodisomy of 4p16.3p15.2
por: Katja, Kloth, et al.
Publicado: (2020)

Primary congenital glaucoma due to paternal uniparental isodisomy of chromosome 2 and CYP1B1 deletion
por: Souzeau, Emmanuelle, et al.
Publicado: (2019)

LRBA Deficiency in a Patient With a Novel Homozygous Mutation Due to Chromosome 4 Segmental Uniparental Isodisomy
por: Soler-Palacín, Pere, et al.
Publicado: (2018)

PML–RARA-RXR Oligomers Mediate Retinoid and Rexinoid/cAMP Cross-Talk in Acute Promyelocytic Leukemia Cell Differentiation
por: Kamashev, Dmitrii, et al.
Publicado: (2004)

Case Report: Co-existence of a novel EXOC4‐TRHDE gene fusion with PML-RARA in acute promyelocytic leukemia
por: Liu, Xiaodong, et al.
Publicado: (2023)

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA
por: Jaffray, Ellis G., et al.
Publicado: (2023)

A Novel Genetic Variant in the WFS1 Gene in a Patient with Partial Uniparental Mero-Isodisomy of Chromosome 4
por: Delvecchio, Maurizio, et al.
Publicado: (2021)

Myeloid Sarcoma Type of Acute Promyelocytic Leukemia With a Cryptic Insertion of RARA Into FIP1L1: The Clinical Utility of NGS and Bioinformatic Analyses
por: Wang, Yongren, et al.
Publicado: (2021)

The increased expression of 14q32 small nucleolar RNA transcripts in promyelocytic leukemia cells is not dependent on PML–RARA fusion gene
por: Cohen, Y, et al.
Publicado: (2012)

The DNA Binding Property of PML/RARA but Not the Integrity of PML Nuclear Bodies Is Indispensable for Leukemic Transformation
por: Liu, Xi, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_eu4t5u5defscribfapbk1fkahg