ModelFinder: Fast Model Selection for Accurate Phylogenetic Estimates

Model-based molecular phylogenetics plays an important role in comparisons of genomic data, and model selection is a key step in all such analyses. We present ModelFinder, a fast model-selection method that greatly improves the accuracy of phylogenetic estimates. The improvement is achieved by incor...

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Autores principales: Kalyaanamoorthy, Subha, Minh, Bui Quang, Wong, Thomas KF, von Haeseler, Arndt, Jermiin, Lars S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453245/
https://www.ncbi.nlm.nih.gov/pubmed/28481363
http://dx.doi.org/10.1038/nmeth.4285
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author Kalyaanamoorthy, Subha
Minh, Bui Quang
Wong, Thomas KF
von Haeseler, Arndt
Jermiin, Lars S
author_facet Kalyaanamoorthy, Subha
Minh, Bui Quang
Wong, Thomas KF
von Haeseler, Arndt
Jermiin, Lars S
author_sort Kalyaanamoorthy, Subha
collection PubMed
description Model-based molecular phylogenetics plays an important role in comparisons of genomic data, and model selection is a key step in all such analyses. We present ModelFinder, a fast model-selection method that greatly improves the accuracy of phylogenetic estimates. The improvement is achieved by incorporating a model of rate-heterogeneity across sites not previously considered in this context, and by allowing concurrent searches of model-space and tree-space.
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spelling pubmed-54532452017-11-08 ModelFinder: Fast Model Selection for Accurate Phylogenetic Estimates Kalyaanamoorthy, Subha Minh, Bui Quang Wong, Thomas KF von Haeseler, Arndt Jermiin, Lars S Nat Methods Article Model-based molecular phylogenetics plays an important role in comparisons of genomic data, and model selection is a key step in all such analyses. We present ModelFinder, a fast model-selection method that greatly improves the accuracy of phylogenetic estimates. The improvement is achieved by incorporating a model of rate-heterogeneity across sites not previously considered in this context, and by allowing concurrent searches of model-space and tree-space. 2017-05-08 2017-06 /pmc/articles/PMC5453245/ /pubmed/28481363 http://dx.doi.org/10.1038/nmeth.4285 Text en Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Kalyaanamoorthy, Subha
Minh, Bui Quang
Wong, Thomas KF
von Haeseler, Arndt
Jermiin, Lars S
ModelFinder: Fast Model Selection for Accurate Phylogenetic Estimates
title ModelFinder: Fast Model Selection for Accurate Phylogenetic Estimates
title_full ModelFinder: Fast Model Selection for Accurate Phylogenetic Estimates
title_fullStr ModelFinder: Fast Model Selection for Accurate Phylogenetic Estimates
title_full_unstemmed ModelFinder: Fast Model Selection for Accurate Phylogenetic Estimates
title_short ModelFinder: Fast Model Selection for Accurate Phylogenetic Estimates
title_sort modelfinder: fast model selection for accurate phylogenetic estimates
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453245/
https://www.ncbi.nlm.nih.gov/pubmed/28481363
http://dx.doi.org/10.1038/nmeth.4285
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