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Short template switch events explain mutation clusters in the human genome

Resequencing efforts are uncovering the extent of genetic variation in humans and provide data to study the evolutionary processes shaping our genome. One recurring puzzle in both intra- and inter-species studies is the high frequency of complex mutations comprising multiple nearby base substitution...

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Detalles Bibliográficos
Autores principales: Löytynoja, Ari, Goldman, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453318/
https://www.ncbi.nlm.nih.gov/pubmed/28385709
http://dx.doi.org/10.1101/gr.214973.116