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Short template switch events explain mutation clusters in the human genome
Resequencing efforts are uncovering the extent of genetic variation in humans and provide data to study the evolutionary processes shaping our genome. One recurring puzzle in both intra- and inter-species studies is the high frequency of complex mutations comprising multiple nearby base substitution...
Autores principales: | Löytynoja, Ari, Goldman, Nick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453318/ https://www.ncbi.nlm.nih.gov/pubmed/28385709 http://dx.doi.org/10.1101/gr.214973.116 |
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