Cargando…
PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX
Maintenance of chromatin homeostasis involves proper delivery of histone variants to the genome. The interplay between different chaperones regulating the supply of histone variants to distinct chromatin domains remains largely undeciphered. We report a role of promyelocytic leukemia (PML) protein i...
Autores principales: | Delbarre, Erwan, Ivanauskiene, Kristina, Spirkoski, Jane, Shah, Akshay, Vekterud, Kristin, Moskaug, Jan Øivind, Bøe, Stig Ove, Wong, Lee H., Küntziger, Thomas, Collas, Philippe |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453325/ https://www.ncbi.nlm.nih.gov/pubmed/28341773 http://dx.doi.org/10.1101/gr.215830.116 |
Ejemplares similares
-
DAXX-dependent supply of soluble (H3.3–H4) dimers to PML bodies pending deposition into chromatin
por: Delbarre, Erwan, et al.
Publicado: (2013) -
The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity
por: Ivanauskiene, Kristina, et al.
Publicado: (2014) -
New players in heterochromatin silencing: histone variant H3.3 and the ATRX/DAXX chaperone
por: Voon, Hsiao P.J., et al.
Publicado: (2016) -
Prepatterning of differentiation-driven nuclear lamin A/C-associated chromatin domains by GlcNAcylated histone H2B
por: Rønningen, Torunn, et al.
Publicado: (2015) -
H3.Y discriminates between HIRA and DAXX chaperone complexes and reveals unexpected insights into human DAXX-H3.3-H4 binding and deposition requirements
por: Zink, Lisa-Maria, et al.
Publicado: (2017)