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qPCR-High resolution melt analysis for drug susceptibility testing of Mycobacterium leprae directly from clinical specimens of leprosy patients

BACKGROUND: Real-Time PCR-High Resolution Melting (qPCR-HRM) analysis has been recently described for rapid drug susceptibility testing (DST) of Mycobacterium leprae. The purpose of the current study was to further evaluate the validity, reliability, and accuracy of this assay for M. leprae DST in c...

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Detalles Bibliográficos
Autores principales:	Araujo, Sergio, Goulart, Luiz Ricardo, Truman, Richard W., Goulart, Isabela Maria B., Vissa, Varalakshmi, Li, Wei, Matsuoka, Masanori, Suffys, Philip, Fontes, Amanda B., Rosa, Patricia S., Scollard, David M., Williams, Diana L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453413/ https://www.ncbi.nlm.nih.gov/pubmed/28570560 http://dx.doi.org/10.1371/journal.pntd.0005506

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