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Extraocular motoneurons of the adult rat show higher levels of vascular endothelial growth factor and its receptor Flk-1 than other cranial motoneurons
Recent studies show a relationship between the deficit of vascular endothelial growth factor (VEGF) and motoneuronal degeneration, such as that occurring in amyotrophic lateral sclerosis (ALS). VEGF delivery protects motoneurons from cell death and delayed neurodegeneration in animal models of ALS....
Autores principales: | Silva-Hucha, Silvia, Hernández, Rosendo G., Benítez-Temiño, Beatriz, Pastor, Ángel M., de la Cruz, Rosa R., Morcuende, Sara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453543/ https://www.ncbi.nlm.nih.gov/pubmed/28570669 http://dx.doi.org/10.1371/journal.pone.0178616 |
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