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Rectal administration of a chlamydial subunit vaccine protects against genital infection and upper reproductive tract pathology in mice
In this study, we tested the hypothesis that rectal immunization with a VCG-based chlamydial vaccine would cross-protect mice against heterologous genital Chlamydia trachomatis infection and Chlamydia-induced upper genital tract pathologies in mice. Female mice were immunized with a C. trachomatis s...
Autores principales: | Pais, Roshan, Omosun, Yusuf, He, Qing, Blas-Machado, Uriel, Black, Carolyn, Igietseme, Joseph U., Fujihashi, Kohtaro, Eko, Francis O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453548/ https://www.ncbi.nlm.nih.gov/pubmed/28570663 http://dx.doi.org/10.1371/journal.pone.0178537 |
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