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SCYL1 does not regulate REST expression and turnover
A recent study identified SCYL1 as one of the components of the oncogenic STP axis, which promotes triple-negative breast cancer by regulating degradation of the REST tumor suppressor. Contrary to the findings of that study, herein we show by using 3 distinct genetic approaches that SCYL1 does not r...
Autores principales: | Gingras, Sebastien, Kuliyev, Emin, Pelletier, Stéphane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453557/ https://www.ncbi.nlm.nih.gov/pubmed/28570664 http://dx.doi.org/10.1371/journal.pone.0178680 |
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