Detection of a microbial metabolite by STING regulates inflammasome activation in response to Chlamydia trachomatis infection

The innate immune system is a critical component of host defence against microbial pathogens, but effective responses require an ability to distinguish between infectious and non-infectious insult to prevent inappropriate inflammation. Using the important obligate intracellular human pathogen Chlamy...

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Detalles Bibliográficos
Autores principales: Webster, Steve J., Brode, Sven, Ellis, Lou, Fitzmaurice, Timothy J., Elder, Matthew J., Gekara, Nelson O., Tourlomousis, Panagiotis, Bryant, Clare, Clare, Simon, Chee, Ronnie, Gaston, Hill J. S., Goodall, Jane C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453623/
https://www.ncbi.nlm.nih.gov/pubmed/28570638
http://dx.doi.org/10.1371/journal.ppat.1006383

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