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Improved efficacy of allergen-specific immunotherapy by JAK inhibition in a murine model of allergic asthma
BACKGROUND: Allergen-specific immunotherapy (AIT) is the only curative treatment for type-1 allergies, but sometimes shows limited therapeutic response as well as local and systemic side effects. Limited control of local inflammation and patient symptoms hampers its widespread use in severe allergic...
Autores principales: | Aguilar-Pimentel, Antonio, Graessel, Anke, Alessandrini, Francesca, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabě de Angelis, Martin, Russkamp, Dennis, Chaker, Adam, Ollert, Markus, Blank, Simon, Gutermuth, Jan, Schmidt-Weber, Carsten B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453633/ https://www.ncbi.nlm.nih.gov/pubmed/28570653 http://dx.doi.org/10.1371/journal.pone.0178563 |
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