Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology

Tuberculosis remains a global pandemic and drives lung matrix destruction to transmit. Whilst pathways driving inflammatory responses in macrophages have been relatively well described, negative regulatory pathways are less well defined. We hypothesised that Mycobacterium tuberculosis (Mtb) specific...

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Detalles Bibliográficos
Autores principales: Brace, Patience T., Tezera, Liku B., Bielecka, Magdalena K., Mellows, Toby, Garay, Diana, Tian, Shuye, Rand, Lucinda, Green, Justin, Jogai, Sanjay, Steele, Andrew J., Millar, Timothy M., Sanchez-Elsner, Tilman, Friedland, Jon S., Proud, Christopher G., Elkington, Paul T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453634/
https://www.ncbi.nlm.nih.gov/pubmed/28570642
http://dx.doi.org/10.1371/journal.ppat.1006367

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