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Intracardiac metastasis of squamous cell carcinoma of the penis
Penile cancer shows variable incidence in different countries with a higher prevalence in developing countries. Squamous cell carcinoma represents the most common histologic type. The seventh decade of life corresponds to the mean age at diagnosis, but it is not an unusual diagnosis among young adul...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
São Paulo, SP: Universidade de São Paulo, Hospital Universitário
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453657/ https://www.ncbi.nlm.nih.gov/pubmed/28584803 http://dx.doi.org/10.4322/acr.2013.035 |
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author | Siqueira, Sheila Aparecida Coelho Tomikawa, Camila Satie |
author_facet | Siqueira, Sheila Aparecida Coelho Tomikawa, Camila Satie |
author_sort | Siqueira, Sheila Aparecida Coelho |
collection | PubMed |
description | Penile cancer shows variable incidence in different countries with a higher prevalence in developing countries. Squamous cell carcinoma represents the most common histologic type. The seventh decade of life corresponds to the mean age at diagnosis, but it is not an unusual diagnosis among young adults. Most cases present as “in situ” neoplasia or loco regional disease; however, systemic disseminated disease occurs via lymphatic and/or hematogeneous routes. The lymph nodes, liver, and lungs are the most frequently involved sites whereas the heart constitutes an exceptional and atypical site for penile cancer metastases. We report a case of a 79-year-old patient who presented a metastatic squamous cell carcinoma of the penis with intracardiac dissemination. The patient had a past history of cardiomyopathy, which required an artificial cardiac pacemaker implantation. He had been treated 1 year before with a partial penectomy but was admitted for emasculation due to the cancer relapse. During the postoperative period, he experienced sudden respiratory distress and died. The autopsy findings showed metastatic disease into the cardiac right chambers, pulmonary tumoral thrombi, and pulmonary hilar involvement. The authors call attention to the possibility of the presence of pacing leads, cardiomyopathy and the altered low blood flow in the right chambers, as predisposing factors for the tumoral seeding in this case. |
format | Online Article Text |
id | pubmed-5453657 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | São Paulo, SP: Universidade de São Paulo, Hospital Universitário |
record_format | MEDLINE/PubMed |
spelling | pubmed-54536572017-06-05 Intracardiac metastasis of squamous cell carcinoma of the penis Siqueira, Sheila Aparecida Coelho Tomikawa, Camila Satie Autops Case Rep Article / Autopsy Case Report Penile cancer shows variable incidence in different countries with a higher prevalence in developing countries. Squamous cell carcinoma represents the most common histologic type. The seventh decade of life corresponds to the mean age at diagnosis, but it is not an unusual diagnosis among young adults. Most cases present as “in situ” neoplasia or loco regional disease; however, systemic disseminated disease occurs via lymphatic and/or hematogeneous routes. The lymph nodes, liver, and lungs are the most frequently involved sites whereas the heart constitutes an exceptional and atypical site for penile cancer metastases. We report a case of a 79-year-old patient who presented a metastatic squamous cell carcinoma of the penis with intracardiac dissemination. The patient had a past history of cardiomyopathy, which required an artificial cardiac pacemaker implantation. He had been treated 1 year before with a partial penectomy but was admitted for emasculation due to the cancer relapse. During the postoperative period, he experienced sudden respiratory distress and died. The autopsy findings showed metastatic disease into the cardiac right chambers, pulmonary tumoral thrombi, and pulmonary hilar involvement. The authors call attention to the possibility of the presence of pacing leads, cardiomyopathy and the altered low blood flow in the right chambers, as predisposing factors for the tumoral seeding in this case. São Paulo, SP: Universidade de São Paulo, Hospital Universitário 2013-12-31 /pmc/articles/PMC5453657/ /pubmed/28584803 http://dx.doi.org/10.4322/acr.2013.035 Text en Copyright © 2013 Autopsy and Case Reports http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed of terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided article is properly cited. |
spellingShingle | Article / Autopsy Case Report Siqueira, Sheila Aparecida Coelho Tomikawa, Camila Satie Intracardiac metastasis of squamous cell carcinoma of the penis |
title | Intracardiac metastasis of squamous cell carcinoma of the penis |
title_full | Intracardiac metastasis of squamous cell carcinoma of the penis |
title_fullStr | Intracardiac metastasis of squamous cell carcinoma of the penis |
title_full_unstemmed | Intracardiac metastasis of squamous cell carcinoma of the penis |
title_short | Intracardiac metastasis of squamous cell carcinoma of the penis |
title_sort | intracardiac metastasis of squamous cell carcinoma of the penis |
topic | Article / Autopsy Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453657/ https://www.ncbi.nlm.nih.gov/pubmed/28584803 http://dx.doi.org/10.4322/acr.2013.035 |
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