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Deletion of P2Y(2) receptor reveals a role for lymphotoxin-α in fatty streak formation()

BACKGROUND: Lymphotoxin alpha (LTα) is expressed in human atherosclerotic lesions and genetic variations in the LTα pathway have been linked to myocardial infarction. Activation of the P2Y(2) nucleotide receptor (P2Y(2)R) regulates the production of LTα. in vitro. We aimed to uncover a potential pat...

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Detalles Bibliográficos
Autores principales: Qian, Shaomin, Hoggatt, April, Jones-Hall, Yava L., Ware, Carl F., Herring, Paul, Seye, Cheikh I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453728/
https://www.ncbi.nlm.nih.gov/pubmed/27355755
http://dx.doi.org/10.1016/j.vph.2016.06.001

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