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Apocynin preserves glutamatergic neurons in the basolateral amygdala in mice with neonatal sevoflurane exposure

BACKGROUND: Neonatal exposure to anesthetics induces neuronal apoptosis and long-term cognitive dysfunction in rodents. We showed that the nicotinamide adenine dinucleotide phosphate-oxidase inhibitor apocynin not only reduces neurotoxicity by decreasing superoxide levels and preventing mitochondria...

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Detalles Bibliográficos
Autores principales: Sun, Zhongliang, Satomoto, Maiko, Adachi, Yushi U, Makita, Koshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Anesthesiologists 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453896/
https://www.ncbi.nlm.nih.gov/pubmed/28580085
http://dx.doi.org/10.4097/kjae.2017.70.3.335