Induction of Colonic Regulatory T Cells by Mesalamine by Activating the Aryl Hydrocarbon Receptor

BACKGROUND & AIMS: Mesalamine is a first-line drug for treatment of inflammatory bowel diseases (IBD). However, its mechanisms are not fully understood. CD4(+) Foxp3(+) regulatory T cells (Tregs) play a potential role in suppressing IBD. This study determined whether the anti-inflammatory activi...

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Detalles Bibliográficos
Autores principales: Oh-oka, Kyoko, Kojima, Yuko, Uchida, Koichiro, Yoda, Kimiko, Ishimaru, Kayoko, Nakajima, Shotaro, Hemmi, Jun, Kano, Hiroshi, Fujii-Kuriyama, Yoshiaki, Katoh, Ryohei, Ito, Hiroyuki, Nakao, Atsuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453907/
https://www.ncbi.nlm.nih.gov/pubmed/28593185
http://dx.doi.org/10.1016/j.jcmgh.2017.03.010

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