Topical Treatment of Rosacea with Ivermectin Inhibits Gene Expression of Cathelicidin Innate Immune Mediators, LL-37 and KLK5, in Reconstructed and Ex Vivo Skin Models

INTRODUCTION: Numerous intrinsic and extrinsic factors have been associated with the pathophysiology of rosacea, including dysregulation of innate immunity. A high level of cathelicidin antimicrobial peptides (e.g., LL-37) has been shown in the facial skin of patients with rosacea. Excessive product...

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Detalles Bibliográficos
Autores principales: Thibaut de Ménonville, Séverine, Rosignoli, Carine, Soares, Estelle, Roquet, Manon, Bertino, Béatrice, Chappuis, Jean-Paul, Defoin-Platel/Chaussade, Claire, Piwnica, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453918/
https://www.ncbi.nlm.nih.gov/pubmed/28243927
http://dx.doi.org/10.1007/s13555-017-0176-3

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