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Divergent Metabolic Regulation of Autophagy and mTORC1—Early Events in Alzheimer’s Disease?
Alzheimer’s disease (AD) is a progressive disease associated with the production and deposition of amyloid β-peptide (Aβ) aggregates and neurofibrillary tangles, which lead to synaptic and neuronal damage. Reduced autophagic flux has been widely associated with the accumulation of autophagic vacuole...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454035/ https://www.ncbi.nlm.nih.gov/pubmed/28626421 http://dx.doi.org/10.3389/fnagi.2017.00173 |