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Rac1 Guides Porf-2 to Wnt Pathway to Mediate Neural Stem Cell Proliferation

The molecular and cellular mechanisms underlying the anti-proliferative effects of preoptic regulator factor 2 (Porf-2) on neural stem cells (NSCs) remain largely unknown. Here, we found that Porf-2 inhibits the activity of ras-related C3 botulinum toxin substrate 1 (Rac1) protein in hippocampus-der...

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Detalles Bibliográficos
Autores principales: Yang, Xi-Tao, Huang, Guo-Hui, Li, Hong-Jiang, Sun, Zhao-Liang, Xu, Nan-Jie, Feng, Dong-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454044/
https://www.ncbi.nlm.nih.gov/pubmed/28626389
http://dx.doi.org/10.3389/fnmol.2017.00172