Longitudinal changes in amyloid positron emission tomography and volumetric magnetic resonance imaging in the nondemented Down syndrome population

INTRODUCTION: Down syndrome (DS) arises from a triplication of chromosome 21, causing overproduction of the amyloid precursor protein and predisposes individuals to early Alzheimer's disease (AD). METHODS: Fifty-two nondemented adults with DS underwent two cycles of carbon 11-labeled Pittsburgh...

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Detalles Bibliográficos
Autores principales: Lao, Patrick J., Handen, Ben L., Betthauser, Tobey J., Mihaila, Iulia, Hartley, Sigan L., Cohen, Annie D., Tudorascu, Dana L., Bulova, Peter D., Lopresti, Brian J., Tumuluru, Rameshwari V., Murali, Dhanabalan, Mathis, Chester A., Barnhart, Todd E., Stone, Charles K., Price, Julie C., Devenny, Darlynne A., Mailick, Marsha R., Klunk, William E., Johnson, Sterling C., Christian, Bradley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Neuroimaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454131/
https://www.ncbi.nlm.nih.gov/pubmed/28603769
http://dx.doi.org/10.1016/j.dadm.2017.05.001

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