Cargando…

Vagal determinants of exercise capacity

Indirect measures of cardiac vagal activity are strongly associated with exercise capacity, yet a causal relationship has not been established. Here we show that in rats, genetic silencing of the largest population of brainstem vagal preganglionic neurons residing in the brainstem's dorsal vaga...

Descripción completa

Detalles Bibliográficos
Autores principales:	Machhada, Asif, Trapp, Stefan, Marina, Nephtali, Stephens, Robert C.M., Whittle, John, Lythgoe, Mark F., Kasparov, Sergey, Ackland, Gareth L., Gourine, Alexander V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454375/ https://www.ncbi.nlm.nih.gov/pubmed/28516907 http://dx.doi.org/10.1038/ncomms15097

Ejemplares similares

Origins of the vagal drive controlling left ventricular contractility
por: Machhada, Asif, et al.
Publicado: (2016)

Cardioprotection evoked by remote ischaemic preconditioning is critically dependent on the activity of vagal pre-ganglionic neurones
por: Mastitskaya, Svetlana, et al.
Publicado: (2012)

Control of ventricular excitability by neurons of the dorsal motor nucleus of the vagus nerve
por: Machhada, Asif, et al.
Publicado: (2015)

Optogenetic Stimulation of Vagal Efferent Activity Preserves Left Ventricular Function in Experimental Heart Failure
por: Machhada, Asif, et al.
Publicado: (2020)

Astrocytes modulate brainstem respiratory rhythm-generating circuits and determine exercise capacity
por: Sheikhbahaei, Shahriar, et al.
Publicado: (2018)

Glia, sympathetic activity and cardiovascular disease
por: Marina, Nephtali, et al.
Publicado: (2016)

Immediate and sustained increases in the activity of vagal preganglionic neurons during exercise and after exercise training
por: Korsak, Alla, et al.
Publicado: (2023)

Brainstem Hypoxia Contributes to the Development of Hypertension in the Spontaneously Hypertensive Rat
por: Marina, Nephtali, et al.
Publicado: (2015)

Peripheral Neural Detection of Danger–Associated and Pathogen–Associated Molecular Patterns
por: Ackland, Gareth L., et al.
Publicado: (2013)

The Role Of Parafacial Neurons In The Control Of Breathing During Exercise
por: Korsak, Alla, et al.
Publicado: (2018)

Volumetric Spatial Correlations of Neurovascular Coupling Studied using Single Pulse Opto-fMRI
por: Christie, Isabel N., et al.
Publicado: (2017)

Distinct cardioprotective mechanisms of immediate, early and delayed ischaemic postconditioning
por: Barsukevich, Veronika, et al.
Publicado: (2014)

Astrocytes monitor cerebral perfusion and control systemic circulation to maintain brain blood flow
por: Marina, Nephtali, et al.
Publicado: (2020)

Purinergic signalling in the rostral ventro-lateral medulla controls sympathetic drive and contributes to the progression of heart failure following myocardial infarction in rats
por: Marina, Nephtali, et al.
Publicado: (2012)

Astrocytes Modulate Baroreflex Sensitivity at the Level of the Nucleus of the Solitary Tract
por: Mastitskaya, Svetlana, et al.
Publicado: (2020)

PPG neurons in the nucleus of the solitary tract modulate heart rate but do not mediate GLP-1 receptor agonist-induced tachycardia in mice
por: Holt, Marie K., et al.
Publicado: (2020)

Cardiopulmonary Exercise Capacity and Preoperative Markers of Inflammation
por: Sultan, Pervez, et al.
Publicado: (2014)

Remote ischaemic pre- and delayed postconditioning – similar degree of cardioprotection but distinct mechanisms
por: Basalay, Marina, et al.
Publicado: (2012)

Hemichannel-mediated release of lactate
por: Karagiannis, Anastassios, et al.
Publicado: (2015)

Vagal Threshold Determination during Incremental Stepwise Exercise in Normoxia and Normobaric Hypoxia
por: Neuls, Filip, et al.
Publicado: (2020)

Respiratory responses to hypercapnia and hypoxia in mice with genetic ablation of Kir5.1 (Kcnj16)
por: Trapp, Stefan, et al.
Publicado: (2011)

The effect of general anaesthetics on brain lactate release
por: Hadjihambi, Anna, et al.
Publicado: (2020)

Expression of Microbial Enzymes in Mammalian Astrocytes to Modulate Lactate Release
por: Vaccari Cardoso, Barbara, et al.
Publicado: (2021)

Mechanosensory Signaling in Astrocytes
por: Turovsky, Egor A., et al.
Publicado: (2020)

Glucagon-like peptide-1 (GLP-1) mediates cardioprotection by remote ischaemic conditioning
por: Basalay, Marina V., et al.
Publicado: (2016)

Signalling properties of inorganic polyphosphate in the mammalian brain
por: Holmström, Kira M., et al.
Publicado: (2013)

Cardiac vagal dysfunction and myocardial injury after non-cardiac surgery: a planned secondary analysis of the measurement of Exercise Tolerance before surgery study
por: Abbott, T.E.F., et al.
Publicado: (2019)

Signal transduction in astrocytes: Localization and release of inorganic polyphosphate
por: Angelova, Plamena R., et al.
Publicado: (2018)

Subclinical cardiopulmonary dysfunction in stage 3 chronic kidney disease
por: Nelson, Alexander, et al.
Publicado: (2016)

Heritability of heart rate recovery and vagal rebound after exercise
por: Nederend, Ineke, et al.
Publicado: (2016)

Remote and Selective Control of Astrocytes by Magnetomechanical Stimulation
por: Yu, Yichao, et al.
Publicado: (2021)

Control of sympathetic vasomotor tone by catecholaminergic C1 neurones of the rostral ventrolateral medulla oblongata
por: Marina, Nephtali, et al.
Publicado: (2011)

Sympathetic autonomic dysfunction and impaired cardiovascular performance in higher risk surgical patients: implications for perioperative sympatholysis
por: Whittle, John, et al.
Publicado: (2015)

Vagal Flexibility during Exercise: Impact of Training, Stress, Anthropometric Measures, and Gender
por: de Souza, Perciliany Martins, et al.
Publicado: (2020)

Mutation profiling in eight cases of vagal paragangliomas
por: Kudryavtseva, Anna V., et al.
Publicado: (2020)

Electrochemical carbon fiber-based technique for simultaneous recordings of brain tissue PO(2), pH, and extracellular field potentials
por: Hosford, Patrick S., et al.
Publicado: (2019)

Determinants of Exercise Capacity in Patients With Hypertrophic Cardiomyopathy
por: Hwang, Ji-won, et al.
Publicado: (2022)

Reduced vagal modulations of heart rate during overwintering in Antarctica
por: Maggioni, Martina A., et al.
Publicado: (2020)

Brain metabolic sensing and metabolic signaling at the level of an astrocyte
por: Marina, Nephtali, et al.
Publicado: (2017)

Prefrontally modulated vagal neuroimmunomodulation is associated with telomere length
por: Ask, Torvald F., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_o3e2devg40kh3pph63jac5i50b