Adenylate kinase hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation

Targeting the specific metabolic phenotypes of colorectal cancer stem cells (CRCSCs) is an innovative therapeutic strategy for colorectal cancer (CRC) patients with poor prognosis and relapse. However, the context-dependent metabolic traits of CRCSCs remain poorly elucidated. Here we report that ade...

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Detalles Bibliográficos
Autores principales: Ji, Yapeng, Yang, Chuanzhen, Tang, Zefang, Yang, Yongfeng, Tian, Yonglu, Yao, Hongwei, Zhu, Xi, Zhang, Zemin, Ji, Jiafu, Zheng, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454382/
https://www.ncbi.nlm.nih.gov/pubmed/28516914
http://dx.doi.org/10.1038/ncomms15308

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