CNS Aquaporin‐4‐specific B cells connect with multiple B‐cell compartments in neuromyelitis optica spectrum disorder

OBJECTIVES: Neuromyelitis optica spectrum disorder (NMOSD) is a severe inflammatory disorder of the central nervous system (CNS) targeted against aquaporin‐4 (AQP4). The origin and trafficking of AQP4‐specific B cells in NMOSD remains unknown. METHODS: Peripheral (n = 7) and splenic B cells (n = 1)...

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Detalles Bibliográficos
Autores principales: Kowarik, Markus C., Astling, David, Gasperi, Christiane, Wemlinger, Scott, Schumann, Hannah, Dzieciatkowska, Monika, Ritchie, Alanna M., Hemmer, Bernhard, Owens, Gregory P., Bennett, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454399/
https://www.ncbi.nlm.nih.gov/pubmed/28589164
http://dx.doi.org/10.1002/acn3.418

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