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An apicobasal gradient of Rac activity determines protrusion form and position

Each cell within a polarized epithelial sheet must align and correctly position a wide range of subcellular structures, including actin-based dynamic protrusions. Using in vivo inducible transgenes that can sense or modify Rac activity, we demonstrate an apicobasal gradient of Rac activity that is r...

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Detalles Bibliográficos
Autores principales: Couto, Africa, Mack, Natalie Ann, Favia, Lucrezia, Georgiou, Marios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454455/
https://www.ncbi.nlm.nih.gov/pubmed/28524861
http://dx.doi.org/10.1038/ncomms15385