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An apicobasal gradient of Rac activity determines protrusion form and position
Each cell within a polarized epithelial sheet must align and correctly position a wide range of subcellular structures, including actin-based dynamic protrusions. Using in vivo inducible transgenes that can sense or modify Rac activity, we demonstrate an apicobasal gradient of Rac activity that is r...
Autores principales: | Couto, Africa, Mack, Natalie Ann, Favia, Lucrezia, Georgiou, Marios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454455/ https://www.ncbi.nlm.nih.gov/pubmed/28524861 http://dx.doi.org/10.1038/ncomms15385 |
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