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Cost-Effectiveness of Intensive Vs. Standard Follow-Up Models for Patients with Breast Cancer in Shiraz, Iran

BACKGROUND: Breast cancer is the most common type of cancer amongst women throughout the world. Currently, there are various follow-up strategies implemented in Iran, which are usually dependent on clinic policies and agreement among the resident oncologists. PURPOSE: A cost-effectiveness analysis w...

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Autores principales: Hatam, Nahid, Ahmadloo, Niloofar, Vazirzadeh, Mina, Jafari, Abdossaleh, Askarian, Mehrdad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454675/
https://www.ncbi.nlm.nih.gov/pubmed/28125878
http://dx.doi.org/10.22034/APJCP.2016.17.12.5309
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author Hatam, Nahid
Ahmadloo, Niloofar
Vazirzadeh, Mina
Jafari, Abdossaleh
Askarian, Mehrdad
author_facet Hatam, Nahid
Ahmadloo, Niloofar
Vazirzadeh, Mina
Jafari, Abdossaleh
Askarian, Mehrdad
author_sort Hatam, Nahid
collection PubMed
description BACKGROUND: Breast cancer is the most common type of cancer amongst women throughout the world. Currently, there are various follow-up strategies implemented in Iran, which are usually dependent on clinic policies and agreement among the resident oncologists. PURPOSE: A cost-effectiveness analysis was performed to assess the cost-effectiveness of intensive follow-up versus standard models for early breast cancer patients in Iran. MATERIALS AND METHODS: This cross sectional study was performed with 382 patients each in the intensive and standard groups. Costs were identified and measured from a payer perspective, including direct medical outlay. To assess the effectiveness of the two follow-up models we used a decision tree along with indicators of detection of recurrence and metastasis, calculating expected costs and effectiveness for both cases; in addition, incremental cost-effectiveness ratios were determined. RESULTS: The results of decision tree showed expected case detection rates of 0.137 and 0.018 and expected costs of US$24,494.62 and US$6,859.27, respectively, for the intensive and standard follow-up models. Tornado diagrams revealed the highest sensitivity to cost increases using the intensive follow-up model with an ICER=US$148,196.2. CONCLUSION: Overall, the results showed that the intensive follow-up method is not cost-effective when compared to the standard model.
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spelling pubmed-54546752017-08-28 Cost-Effectiveness of Intensive Vs. Standard Follow-Up Models for Patients with Breast Cancer in Shiraz, Iran Hatam, Nahid Ahmadloo, Niloofar Vazirzadeh, Mina Jafari, Abdossaleh Askarian, Mehrdad Asian Pac J Cancer Prev Research Article BACKGROUND: Breast cancer is the most common type of cancer amongst women throughout the world. Currently, there are various follow-up strategies implemented in Iran, which are usually dependent on clinic policies and agreement among the resident oncologists. PURPOSE: A cost-effectiveness analysis was performed to assess the cost-effectiveness of intensive follow-up versus standard models for early breast cancer patients in Iran. MATERIALS AND METHODS: This cross sectional study was performed with 382 patients each in the intensive and standard groups. Costs were identified and measured from a payer perspective, including direct medical outlay. To assess the effectiveness of the two follow-up models we used a decision tree along with indicators of detection of recurrence and metastasis, calculating expected costs and effectiveness for both cases; in addition, incremental cost-effectiveness ratios were determined. RESULTS: The results of decision tree showed expected case detection rates of 0.137 and 0.018 and expected costs of US$24,494.62 and US$6,859.27, respectively, for the intensive and standard follow-up models. Tornado diagrams revealed the highest sensitivity to cost increases using the intensive follow-up model with an ICER=US$148,196.2. CONCLUSION: Overall, the results showed that the intensive follow-up method is not cost-effective when compared to the standard model. West Asia Organization for Cancer Prevention 2016 /pmc/articles/PMC5454675/ /pubmed/28125878 http://dx.doi.org/10.22034/APJCP.2016.17.12.5309 Text en Copyright: © Asian Pacific Journal of Cancer Prevention http://creativecommons.org/licenses/BY-SA/4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
spellingShingle Research Article
Hatam, Nahid
Ahmadloo, Niloofar
Vazirzadeh, Mina
Jafari, Abdossaleh
Askarian, Mehrdad
Cost-Effectiveness of Intensive Vs. Standard Follow-Up Models for Patients with Breast Cancer in Shiraz, Iran
title Cost-Effectiveness of Intensive Vs. Standard Follow-Up Models for Patients with Breast Cancer in Shiraz, Iran
title_full Cost-Effectiveness of Intensive Vs. Standard Follow-Up Models for Patients with Breast Cancer in Shiraz, Iran
title_fullStr Cost-Effectiveness of Intensive Vs. Standard Follow-Up Models for Patients with Breast Cancer in Shiraz, Iran
title_full_unstemmed Cost-Effectiveness of Intensive Vs. Standard Follow-Up Models for Patients with Breast Cancer in Shiraz, Iran
title_short Cost-Effectiveness of Intensive Vs. Standard Follow-Up Models for Patients with Breast Cancer in Shiraz, Iran
title_sort cost-effectiveness of intensive vs. standard follow-up models for patients with breast cancer in shiraz, iran
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454675/
https://www.ncbi.nlm.nih.gov/pubmed/28125878
http://dx.doi.org/10.22034/APJCP.2016.17.12.5309
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