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In Vitro and In Vivo Anticancer Activity of Gimatecan against Hepatocellular Carcinoma

OBJECTIVE: Gimatecan is a new camptothecin (CPT) analogue that inhibits tumor growth by targeting DNA topoisomerase I (TOP I) and introducing strong and persistent DNA cleavage. Anti-tumor activity has been demonstrated with a wide range of solid tumors in previous preclinical and clinical studies....

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Detalles Bibliográficos
Autores principales:	Zhao, Youna, Lau, Lit-Fui, Dai, Xiangrong, Li, Benjamin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454685/ https://www.ncbi.nlm.nih.gov/pubmed/28030910 http://dx.doi.org/10.22034/APJCP.2016.17.11.4853

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