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Significance of Wild-Type p53 Signaling in Suppressing Apoptosis in Response to Chemical Genotoxic Agents: Impact on Chemotherapy Outcome

Our genomes are subject to potentially deleterious alterations resulting from endogenous sources (e.g., cellular metabolism, routine errors in DNA replication and recombination), exogenous sources (e.g., radiation, chemical agents), and medical diagnostic and treatment applications. Genome integrity...

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Detalles Bibliográficos
Autores principales:	Mirzayans, Razmik, Andrais, Bonnie, Kumar, Piyush, Murray, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454841/ https://www.ncbi.nlm.nih.gov/pubmed/28452953 http://dx.doi.org/10.3390/ijms18050928

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