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Hypoxia Mediates Differential Response to Anti-EGFR Therapy in HNSCC Cells

Despite advances in the head and neck squamous cell carcinoma (HNSCC) treatment modalities, drug resistance and cancer recurrence are often reported. Hypoxia signaling through hypoxia-inducible factor 1 (HIF-1) promotes angiogenesis and metastasis by inducing epithelial-mesenchymal-transition (EMT)....

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Detalles Bibliográficos
Autores principales:	Wiechec, Emilia, Hansson, Katharina Tiefenböck, Alexandersson, Lisa, Jönsson, Jan-Ingvar, Roberg, Karin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454856/ https://www.ncbi.nlm.nih.gov/pubmed/28468237 http://dx.doi.org/10.3390/ijms18050943

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