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Folic Acid Supplementation Delays Atherosclerotic Lesion Development by Modulating MCP1 and VEGF DNA Methylation Levels In Vivo and In Vitro

The pathogenesis of atherosclerosis has been partly acknowledged to result from aberrant epigenetic mechanisms. Accordingly, low folate levels are considered to be a contributing factor to promoting vascular disease because of deregulation of DNA methylation. We hypothesized that increasing the leve...

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Detalles Bibliográficos
Autores principales: Cui, Shanshan, Li, Wen, Lv, Xin, Wang, Pengyan, Gao, Yuxia, Huang, Guowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454903/
https://www.ncbi.nlm.nih.gov/pubmed/28475147
http://dx.doi.org/10.3390/ijms18050990

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